Desflurane Inhalation Provide Cardiovascular Stability During Intubation but Prevention of Rocuronium Injection Pain
고현민, 홍훈표, 윤지영, 윤지욱, 이도원, 김철홍,
소속 상세정보
고현민 ( Ko Hyun-Min ) - 부산대학교 치의학전문대학원 치과마취통증학교실
홍훈표 ( Hong Hun-Pyo ) - 부산대학교 치의학전문대학원 치과마취통증학교실
윤지영 ( Yoon Ji-Young ) - 부산대학교 치의학전문대학원 치과마취통증학교실
윤지욱 ( Yoon Ji-Uk ) - 부산대학교 의학전문대학원 마취통증의학교실
이도원 ( Lee Do-Won ) - 부산대학교 의학전문대학원 마취통증의학교실
김철홍 ( Kim Cheul-Hong ) - 부산대학교 치의학전문대학원 치과마취통증학교실
KMID : 0980220130130030117
Abstract
Background: Desflurane has very short induction time because its physical characteristics. But its pungent odor and tendency to irritate the upper airway make it unsuitable for induction of anesthesia. This study was performed to determine what time is prefer to start the desflurane inhalation.
Methods: Forty adults (17-45 years) were enrolled in a randomized, double-blind study. Twenty start desflurane inhalation just after loss of consciousness, and the others received desflurane after intubation. We monitored vital signs, BIS, desflurane concentration, rocuronium injection pain response, and airway irritation signs.
Results: The demographic data were not different two groups. Early inhalation group showed more stable cardiovascular response than that of late inhalation group. But rocuronium injection pain response and airway irritation sings were not different between two groups.
Conclusions: Early inhalation of desflurane (6 vol%) just after loss of consciousness attenuates cardiovascular responses during intubation.
키워드
Airway irritation; Cardiovascular stability; Desflurane inhalation; Rocuronium injection pain
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